PICCININI, Marco
 Distribuzione geografica
Continente #
NA - Nord America 3.168
EU - Europa 2.393
AS - Asia 815
AF - Africa 25
OC - Oceania 12
SA - Sud America 8
Continente sconosciuto - Info sul continente non disponibili 2
Totale 6.423
Nazione #
US - Stati Uniti d'America 3.100
CN - Cina 484
IT - Italia 444
SE - Svezia 345
IE - Irlanda 304
DE - Germania 255
UA - Ucraina 225
FR - Francia 190
FI - Finlandia 164
GB - Regno Unito 141
KR - Corea 132
AT - Austria 130
BE - Belgio 68
CA - Canada 66
PL - Polonia 57
VN - Vietnam 49
IN - India 47
JP - Giappone 30
SN - Senegal 14
IR - Iran 13
NL - Olanda 13
UZ - Uzbekistan 13
AU - Australia 12
ES - Italia 12
TW - Taiwan 10
HK - Hong Kong 9
MY - Malesia 6
PK - Pakistan 6
BR - Brasile 5
CZ - Repubblica Ceca 5
GR - Grecia 5
BG - Bulgaria 4
CH - Svizzera 4
DK - Danimarca 4
EG - Egitto 4
HR - Croazia 4
ID - Indonesia 4
RU - Federazione Russa 4
CI - Costa d'Avorio 3
IQ - Iraq 3
RO - Romania 3
RS - Serbia 3
TR - Turchia 3
EU - Europa 2
GE - Georgia 2
HU - Ungheria 2
IL - Israele 2
MK - Macedonia 2
NG - Nigeria 2
NO - Norvegia 2
AR - Argentina 1
BZ - Belize 1
CL - Cile 1
CO - Colombia 1
EE - Estonia 1
IS - Islanda 1
MU - Mauritius 1
MX - Messico 1
PT - Portogallo 1
SA - Arabia Saudita 1
SG - Singapore 1
ZA - Sudafrica 1
Totale 6.423
Città #
Chandler 545
Beijing 360
Dublin 303
Jacksonville 188
Ann Arbor 181
Nyköping 146
Torino 144
Dearborn 135
Houston 130
Vienna 129
Medford 103
Villeurbanne 103
Woodbridge 96
Princeton 92
Fremont 89
Fairfield 74
Wilmington 70
Brussels 64
Warsaw 52
Milan 47
Boston 42
Ashburn 41
Boardman 35
Seattle 35
Redwood City 34
Washington 31
Cambridge 30
Pisa 30
Dong Ket 28
Toronto 24
Ottawa 19
Verona 19
Guangzhou 14
Falls Church 12
Norwalk 12
Hefei 11
Lachine 11
Nanjing 11
Turin 10
Detroit 9
Mountain View 9
Taipei 9
Kunming 7
Nürnberg 7
Riverside 7
Düsseldorf 6
Edinburgh 6
Hangzhou 6
La Jolla 6
Munich 6
Paris 6
Piemonte 6
Shanghai 6
Shenyang 6
Sherwood Park 6
Zhengzhou 6
Bari 5
Chengdu 5
Hebei 5
Leinì 5
Otemae 5
Redmond 5
Rome 5
Tokyo 5
Changsha 4
Jakarta 4
Jinan 4
Los Angeles 4
Sassari 4
Sesto Fiorentino 4
Wuhan 4
Arlington 3
Auburn Hills 3
Baotou 3
Berlin 3
Bologna 3
Brussel 3
Changchun 3
Como 3
Copenhagen 3
Durham 3
Ellicott City 3
Fazal 3
Kuala Lumpur 3
London 3
Madrid 3
Malappuram 3
Nanchang 3
San Diego 3
San Francisco 3
San Jose 3
San Mateo 3
Abuja 2
Aci Catena 2
Atlanta 2
Basel 2
Batu Caves 2
Beachwood 2
Belgrade 2
Bridge 2
Totale 3.761
Nome #
TDP-43 Redistribution Is an Early Event in Sporadic Amyotrophic Lateral Sclerosis 266
Exposure of neuroblastoma cell lines to imatinib results in the upregulation of the CDK inhibitor p27KIP1 as a consequence of c-Abl inhibition 241
PROCEEDINGS OF THE MERCK & ELSEVIER YOUNG CHEMISTSSYMPOSIUM 212
Design, synthesis, biological evaluation and X-ray structural studies of potent human dihydroorotate dehydrogenase inhibitors based on hydroxylated azole scaffolds 151
Development of Potent Human Dihydroorotate Dehydrogenase Inhibitors Able to Induces Myeloid Differentiation 149
N-Acetyl-3-aminopyrazoles block the non canonical NF-kB cascade by selectively inhibiting NIK 117
Characterization of the chymotriptic activity of the 26 S protease from bovine brain. 111
Increased cytoplasmic mislocalization of TAR DNA binding protein 43 (TDP-43) in circulating lymphomonocytes of ALS patients recapitulates the major dysfunction featuring motor neurons in the disease. 107
4-Hydroxy-N-[3,5-bis(trifluoromethyl)phenyl]-1,2,5-thiadiazole-3-carboxamide: a novel inhibitor of the canonical NF-κB cascade 107
TOWARD A BIOISOSTERIC ALKAEST – APPLICATION TO THE BIOISOSTERIC MODULATION OF IMD-0354 103
A defective L_MAG (large myelin-associated glycoprotein) is responsible for an adult-onset autosomal dominant orthochromatic leukodystrophy 101
The expression pattern of TAR DNA-binding protein 43 (TDP-43) in peripheral blood mononuclear cells (PBMC) in individuals affected by amyotrophific lateral sclerosis (ALS) and their healthy relatives 100
IκB kinase β is required for activation of NF-κB and AP-1 in CD3/CD28-stimulated primary CD4(+) T cells. 100
In vitro myeloid differentiation using a new generation of potent human dihydroorotate dehydrogenase (hDHODH) inhibitors 100
Acid soluble, short chain esterified and free carnitine in the liver, heart, muscle and brain of pre and post hatched chicks. 99
Targeting Myeloid Differentiation Using Potent 2-Hydroxypyrazolo[1,5- a]pyridine Scaffold-Based Human Dihydroorotate Dehydrogenase Inhibitors 98
Targeting the human Dihydroorotate Dehydrogenase (hDHODH) by a Scaffold Hopping Bioisosteric approach using Hydroxylated Pentatomic Heterocycles 94
Myelin is involved in Niemann-Pick disease 90
Affinity purification and characterization of protein gene product 9.5 (PGP9.5) from retina. 89
Towards a Bioisosteric Alkaest: application to the bioisosteric modulation of IMD-0354 85
Targeting the human Dihydroorotate Dehydrogenase (hDHODH) by combination of in-silico ligand/structural pharmacophore models and scaffold hopping bioisosteric approaches 85
An approach to the timing of altered localization of TDP-43 in ALS motor neurons during disease progression 84
Targeting the human Dihydroorotate Dehydrogenase (hDHODH) by a Scaffold Hopping Bioisosteric approach using Hydroxylated Pentaatomic Heterocycles 83
Nitrooxyacyl Derivatives of Salicylic Acid: Aspirin-Like Molecules that Covalently Inactivate Cyclooxygenase-1 82
TDP-43 redistribution is an early event in sporadic amyotrophic lateral sclerosis 81
Myelin involvement in Niemann-Pick disease type A 80
Alterations of myelin-specific proteins and sphingolipids characterize the brains of acid sphingomyelinase-deficient mice, an animal model of niemannpick disease type A 80
Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5- a]pyridine Scaffold: SAR of the Biphenyl Moiety 80
Cytoplasmic accumulation of TDP-43 in circulating lymphomonocytes of ALS patients with and without TARDBP mutations 78
Myelin-associated glycoprotein is altered in a familial orthochromatic leukodystrophy 77
The insulin signal and its effects on the pyruvate dehydrogenase complex in circulating lymphocytes of obese children. 75
In vitro myeloid differentiation using a new generation of potent human dihydroorotate dehydrogenase inhibitors 75
Insulin modulation of pyruvate dehydrogenase in human circulating lymphocytes. 74
Myelin-associated glycoprotein is altered in a familial late-onset orthochromatic leukodystrophy 74
Detection of a Proteasome in Pneumocystis carinii and its Modulation by Specific Proteasome Inhibitors 74
The behaviour of pyruvate dehydrogenase in circulating lymphocytes from diabetic children 74
Dysfunctions in N_CAM and unexpected accumulation of PSA_NCAM in brain of Autosomal dominant adult onset leukodystrophy (ADLD) 74
The HIV protease inhibitors nelfinavir and saquinavir, but not a variety of HIV reverse transcriptase inhibitors, adversely affect human proteasome function 73
Deregulated Sphingolipid Metabolism and Membrane Organization in Neurodegenerative Disorders 73
In obese individuals dexfenfluramine corrects molecular derangements reflecting insulin resistance 73
Modulazione della glicolisi in cellule endoteliali umane sottoposte ad elevate concentrazioni di glucosio in vitro. 71
Targeting myeloid differentiation using potent human dihydroorotate dehydrogenase (hDHODH) inhibitors 71
Emerging therapies for acute myeloid leukaemia using hDHODH inhibitors 70
Modulazione della glicolisi in cellule endoteliali umane sottoposte ad elevate concentrazioni di glucosio in vitro. 69
Effect of sulfonylurea agents on pyruvate dehydrogenase activity in circulating lymphocytes from patients with non-insulin-dependent diabetes mellitus (NIDDM). 69
Pregnancy induces molecular alterations reflecting impaired insulin control over glucose oxidative pathways that only in women with a family history for type 2 diabetes last beyond pregnancy 68
Down-regulation of pyruvate dehydrogenase phosphatase in obese subjects is a defect that signals insulin resistance 67
Characterization of the 20S proteasome in human glioblastomas 66
Expression pattern of the 20S proteasome subunits following T cell activation 66
Biomarker for Frontotemporal Lobar Degeneration (FTLD) with TDP-43 Pathology: the Circulating Lymphocytes 65
null 65
Altered sphingolipid metabolism in acidic sphingomyelinase knocout mice, an animal model for Niemann-Pick disease type A 64
Distribution of protein gene product 9.5 (PGP 9.5) in the vertebrate retina: evidence that immunoreactivity is restricted to mammalian horizontal and ganglion cells. 62
Myelin-associated glycoprotein is defective in a familial orthochromatic leukodystrophy 62
Discovery of new NIK inhibitors by Structure-Based Drug Design 62
Levels of carnitine and glycogen in rabbit tissues during development. 62
Derangements of pyruvate dehydrogenase in circulating lymphocytes of NIDDM patients and their healthy offspring. 61
Novel dysfunctions at the origin of hypomyelination, a feature of Niemann Pick type A 60
The molecular basis of the hypomyelination characterizing the brains of sphingomyelinase-deficient mice, an animal model of Niemann-Pick disease type A 59
Myelin-associated glycoprotein is defective in a familail orthochromatic leukodystrophy 58
Reduced cellular Ca(2+) availability enhances TDP-43 cleavage by apoptotic caspases. 58
Modulation of glycolysis by high glucose in cultured human endothelial cells. 58
Alterations of protein and lipid patterns in brain white matter of ASMKO mice, the animal model of Niemann-Pick disease type A 56
Type I collagen limits VEGFR-2 signaling by a SHP2 protein-tyrosine phosphatase-dependent mechanism 1 53
In CD28-costimulated human naïve CD4(+) T cells, I-κB kinase controls the expression of cell cycle regulatory proteins via interleukin-2-independent mechanisms 53
G proteins and regulation of pyruvate dehydrogenase activity by insulin in human circulating lymphocytes. 52
Pyruvate dehydrogenase activation by insulin in human circulating lymphocytes and the possible pathway involved. 50
Insulin resistance in obese subjects and newly diagnosed NIDDM patients and derangements of pyruvate dehydrogenase in their circulating lymphocytes 49
Reduced expression of proteins characterizing myelin sheaths in brain of acid sphingomyelinase-deficinet mice, the animal model of Niemann-Pick disease type A 48
Proteasomes are a target of the anti-tumour drug vinblastine 47
Enhanced blood insulin overcomes pyruvate dehydrogenase derangements that reflect systemic insulin resistance in obese adolescents. 46
Proteasomes as drug targets. 46
Structural and functional properties of proteasomes purified from the human kidney 43
Purificazione e caratterizzazione di proteasomi renali umani 43
Modulation of glycolysis by high glucose in cultured human endothelial cells. 43
Proteins targeted by ubiquitin and the ubiquitin-proteasome system in malignant gliomas 42
Immunoproteasome Activity in the Nervous System 41
Structural and functional characterization of 20S and 26S proteasomes from bovine brain. 41
Multidiscliplinary approach to cause and pathogenesis of an adult onset autosomal dominant orthochromatic leukodystrophy 41
The Ubiquitin Proteasome System in The Pathobiology of Human Gliomas (Chapter 36) 39
Primary structure and oxygen-binding properties of the hemoglobin from the lesser hedgehog tenrec (Echinops telfairi, Zalambdodonta). Evidence for phylogenetic isolation. 37
The human 26S proteasome is a target of antiretroviral agents. 37
Molecular effects of sulphonylurea agents in circulating lymphocytes of patients with non-insulin-dependent diabetes mellitus. 37
The Ubiquitin Proteasome System in The Pathobiology of Human Gliomas in 34
Interferon-gamma-inducible subunits are incorporated in human brain 20S proteasome. 34
New human dihydroorotate dehydrogenase inhibitors able to restore myeloid differentiation in AML 32
Targeting the human Dihydroorotate Dehydrogenase (hDHODH) by a Scaffold Hopping Bioisosteric approach using Hydroxylated Pentatomic Heterocycles 32
N-CAM Dysfunction and Unexpected Accumulation of PSA-NCAM in Brain of Adult-Onset Autosomal-Dominant Leukodystrophy. 28
Primary structure and oxygen-binding properties of the hemoglobin from guanaco (Lama guanaco, Tylopoda). 25
Targeting Acute Myelogenous Leukemia Using Potent Human Dihydroorotate Dehydrogenase Inhibitors Based on the 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold: SAR of the Aryloxyaryl Moiety 24
Toward a Bioisosteric Alkahest: Targeting the human Dihydroorotate Dehydrogenase (hDHODH) by a Scaffold Hopping Bioisosteric approach using Hydroxylated Pentatomic Heterocycles 21
AMPK activation attenuates HER3 upregulation and Neuregulin-Mediated rescue of cell proliferation in HER2-Overexpressing breast cancer cell lines exposed to lapatinib 10
Totale 6.666
Categoria #
all - tutte 14.841
article - articoli 0
book - libri 0
conference - conferenze 6.569
curatela - curatele 0
other - altro 0
patent - brevetti 0
selected - selezionate 0
volume - volumi 0
Totale 21.410


Totale Lug Ago Sett Ott Nov Dic Gen Feb Mar Apr Mag Giu
2018/2019600 0 0 0 32 22 97 30 84 36 132 105 62
2019/2020946 47 73 75 71 63 171 113 42 74 109 72 36
2020/2021755 106 67 52 40 71 33 65 26 124 55 42 74
2021/2022965 26 16 52 57 32 49 55 36 19 100 311 212
2022/20231.527 163 164 30 168 125 383 126 94 134 41 67 32
2023/2024297 95 148 54 0 0 0 0 0 0 0 0 0
Totale 6.666