GIANQUINTO, Eleonora
GIANQUINTO, Eleonora
SCIENZA E TECNOLOGIA DEL FARMACO
4-amino-1,2,4-triazole-3-thione as a promising scaffold for the inhibition of serine and metallo-β-lactamases
2020-01-01 Linciano P.; Gianquinto E.; Montanari M.; Maso L.; Bellio P.; Cebrian-Sastre E.; Celenza G.; Blazquez J.; Cendron L.; Spyrakis F.; Tondi D.
Binding of androgen-and estrogen-like flavonoids to their cognate (Non)nuclear receptors: A comparison by computational prediction
2021-01-01 D'arrigo G.; Gianquinto E.; Rossetti G.; Cruciani G.; Lorenzetti S.; Spyrakis F.
BROAD SPECTRUM METALLO beta-LACTAMASES INHIBITORS: NEW TOOLS AGAINST CLINICALLY-RELEVANT CARBAPENEMASES
2022-01-01 Lazzarato, L.; Failla, M.; Gianquinto, E.; Bersani, M.; Bertarini, L.; Verri, A.; Vascon, F.; Sannio, F.; Verdirosa, F.; Beatrice, N.; De Luca, F.; Costi, M.P.; Cruciani, G.; Docquier, J.D.; Cendron, L.; Spyrakis, F.; Tondi, D.
Can we exploit β-lactamases intrinsic dynamics for designing more effective inhibitors?
2020-01-01 Gianquinto E.; Tondi D.; D'arrigo G.; Lazzarato L.; Spyrakis F.
Chemical modulation of the 1-(Piperidin-4-yl)-1,3-dihydro-2h-benzo[d]imidazole-2-one scaffold as a novel NLRP3 inhibitor
2021-01-01 Gastaldi S.; Boscaro V.; Gianquinto E.; Sandall C.F.; Giorgis M.; Marini E.; Blua F.; Gallicchio M.; Spyrakis F.; Macdonald J.A.; Bertinaria M.
Cryo-EM structures of staphylococcal IsdB bound to human hemoglobin reveal the process of heme extraction
2022-01-01 De Bei, Omar; Marchetti, Marialaura; Ronda, Luca; Gianquinto, Eleonora; Lazzarato, Loretta; Chirgadze, Dimitri Y; Hardwick, Steven W; Cooper, Lee R; Spyrakis, Francesca; Luisi, Ben F; Campanini, Barbara; Bettati, Stefano
Design and synthesis of encorafenib-based BRAF-V600E degraders
2022-01-01 Federica Blua, Marco Marino, Simone Gastaldi, Federica Maione, Eleonora Gianquinto, Federica Di Nicolantonio, Massimo Bertinaria
Discovery of a novel 1,3,4-oxadiazol-2-one-based NLRP3 inhibitor as a pharmacological agent to mitigate cardiac and metabolic complications in an experimental model of diet-induced metaflammation
2023-01-01 Gastaldi, Simone; Rocca, Carmine; Gianquinto, Eleonora; Granieri, Maria Concetta; Boscaro, Valentina; Blua, Federica; Rolando, Barbara; Marini, Elisabetta; Gallicchio, Margherita; De Bartolo, Anna; Romeo, Naomi; Mazza, Rosa; Fedele, Francesco; Pagliaro, Pasquale; Penna, Claudia; Spyrakis, Francesca; Bertinaria, Massimo; Angelone, Tommaso
Evaluation of Porcine and Aspergillus oryzae α-Amylases as Possible Model for the Human Enzyme
2022-01-01 Mauro Marengo, Davide Pezzilli, Eleonora Gianquinto, Alex Fissore, Simonetta Oliaro-Bosso, Barbara Sgorbini, Francesca Spyrakis, Salvatore Adinolfi
Exploring Ligand Binding Domain Dynamics in the NRs Superfamily
2022-01-01 D'Arrigo, Giulia; Autiero, Ida; Gianquinto, Eleonora; Siragusa, Lydia; Baroni, Massimo; Cruciani, Gabriele; Spyrakis, Francesca
Fluorescent Nitric Oxide Photodonors Based on BODIPY and Rhodamine Antennae
2019-01-01 Parisi C.; Failla M.; Fraix A.; Rolando B.; Gianquinto E.; Spyrakis F.; Gazzano E.; Riganti C.; Lazzarato L.; Fruttero R.; Gasco A.; Sortino S.
In the search for new NLRP3 inhibitors: chemical modulation of the 1-(piperidin-4-yl)-1,3-dihydro-2 Hbenzo[d]imidazole-2-one scaffold
2021-01-01 Simone Gastaldi, Valentina Boscaro, Eleonora Gianquinto, Christina F. Sandall, Marta Giorgis, Elisabetta Marini, Federica Blua, Margherita Gallicchio, Francesca Spyrakis, Justin A. MacDonald, Massimo Bertinaria
Interaction of human hemoglobin and semi-hemoglobins with the Staphylococcus aureus hemophore IsdB: a kinetic and mechanistic insight
2019-01-01 Gianquinto E.; Moscetti I.; De Bei O.; Campanini B.; Marchetti M.; Luque F.J.; Cannistraro S.; Ronda L.; Bizzarri A.R.; Spyrakis F.; Bettati S.
Investigation into the Use of Encorafenib to Develop Potential PROTACs Directed against BRAFV600E Protein
2022-01-01 Marini, Elisabetta; Marino, Marco; Gionfriddo, Giulia; Maione, Federica; Pandini, Marta; Oddo, Daniele; Giorgis, Marta; Rolando, Barbara; Blua, Federica; Gastaldi, Simone; Marchiò, Serena; Kovachka, Sandra; Spyrakis, Francesca; Gianquinto, Eleonora; Di Nicolantonio, Federica; Bertinaria, Massimo
Iron metabolism at the interface between host and pathogen: From nutritional immunity to antibacterial development
2020-01-01 Marchetti M.; De Bei O.; Bettati S.; Campanini B.; Kovachka S.; Gianquinto E.; Spyrakis F.; Ronda L.
N-[1,3-Dialkyl(aryl)-2-oxoimidazolidin-4-ylidene]-aryl(alkyl)sulphonamides as Novel Selective Human Cannabinoid Type 2 Receptor (hCB2R) Ligands; Insights into the Mechanism of Receptor Activation/Deactivation
2022-01-01 Gianquinto, Eleonora; Sodano, Federica; Rolando, Barbara; Kostrzewa, Magdalena; Allarà, Marco; Mahmoud, Ali Mokhtar; Kumar, Poulami; Spyrakis, Francesca; Ligresti, Alessia; Chegaev, Konstantin
Natural products as novel scaffolds for the design of glycogen synthase kinase 3β inhibitors
2022-01-01 Montanari, Serena; Seidl, Claudia; Davani, Lara; Gianquinto, Eleonora; Emrichova, Eliska; Terenzi, Cristina; Andrisano, Vincenza; De Simone, Angela
NLRP3 monomer functional dynamics: From the effects of allosteric binding to implications for drug design
2023-01-01 Casali, Emanuele; Serapian, Stefano A; Gianquinto, Eleonora; Castelli, Matteo; Bertinaria, Massimo; Spyrakis, Francesca; Colombo, Giorgio
Repurposing the trypanosomatidic gsk kinetobox for the inhibition of parasitic pteridine and dihydrofolate reductases
2021-01-01 Santucci M.; Luciani R.; Gianquinto E.; Pozzi C.; Di Pisa F.; Dello Iacono L.; Landi G.; Tagliazucchi L.; Mangani S.; Spyrakis F.; Costi M.P.
Selective delivery of pentamidine toward cancer cells by self-assembled nanoparticles
2022-01-01 Andreana, I; Gazzano, E; Gianquinto, E; Piatti, G; Bincoletto, V; Kryza, D; Lollo, G; Spyrakis, F; Riganti, C; Arpicco, S; Stella, B
| Titolo | Data di pubblicazione | Autore(i) | File |
|---|---|---|---|
| 4-amino-1,2,4-triazole-3-thione as a promising scaffold for the inhibition of serine and metallo-β-lactamases | 2020 | Linciano P.; Gianquinto E.; Montanari M.; Maso L.; Bellio P.; Cebrian-Sastre E.; Celenza G.; Blazquez J.; Cendron L.; Spyrakis F.; Tondi D. | |
| Binding of androgen-and estrogen-like flavonoids to their cognate (Non)nuclear receptors: A comparison by computational prediction | 2021 | D'arrigo G.; Gianquinto E.; Rossetti G.; Cruciani G.; Lorenzetti S.; Spyrakis F. | |
| BROAD SPECTRUM METALLO beta-LACTAMASES INHIBITORS: NEW TOOLS AGAINST CLINICALLY-RELEVANT CARBAPENEMASES | 2022 | Lazzarato, L.; Failla, M.; Gianquinto, E.; Bersani, M.; Bertarini, L.; Verri, A.; Vascon, F.; Sannio, F.; Verdirosa, F.; Beatrice, N.; De Luca, F.; Costi, M.P.; Cruciani, G.; Docquier, J.D.; Cendron, L.; Spyrakis, F.; Tondi, D. | |
| Can we exploit β-lactamases intrinsic dynamics for designing more effective inhibitors? | 2020 | Gianquinto E.; Tondi D.; D'arrigo G.; Lazzarato L.; Spyrakis F. | |
| Chemical modulation of the 1-(Piperidin-4-yl)-1,3-dihydro-2h-benzo[d]imidazole-2-one scaffold as a novel NLRP3 inhibitor | 2021 | Gastaldi S.; Boscaro V.; Gianquinto E.; Sandall C.F.; Giorgis M.; Marini E.; Blua F.; Gallicchio M.; Spyrakis F.; Macdonald J.A.; Bertinaria M. | |
| Cryo-EM structures of staphylococcal IsdB bound to human hemoglobin reveal the process of heme extraction | 2022 | De Bei, Omar; Marchetti, Marialaura; Ronda, Luca; Gianquinto, Eleonora; Lazzarato, Loretta; Chirgadze, Dimitri Y; Hardwick, Steven W; Cooper, Lee R; Spyrakis, Francesca; Luisi, Ben F; Campanini, Barbara; Bettati, Stefano | |
| Design and synthesis of encorafenib-based BRAF-V600E degraders | 2022 | Federica Blua, Marco Marino, Simone Gastaldi, Federica Maione, Eleonora Gianquinto, Federica Di Nicolantonio, Massimo Bertinaria | |
| Discovery of a novel 1,3,4-oxadiazol-2-one-based NLRP3 inhibitor as a pharmacological agent to mitigate cardiac and metabolic complications in an experimental model of diet-induced metaflammation | 2023 | Gastaldi, Simone; Rocca, Carmine; Gianquinto, Eleonora; Granieri, Maria Concetta; Boscaro, Valentina; Blua, Federica; Rolando, Barbara; Marini, Elisabetta; Gallicchio, Margherita; De Bartolo, Anna; Romeo, Naomi; Mazza, Rosa; Fedele, Francesco; Pagliaro, Pasquale; Penna, Claudia; Spyrakis, Francesca; Bertinaria, Massimo; Angelone, Tommaso | |
| Evaluation of Porcine and Aspergillus oryzae α-Amylases as Possible Model for the Human Enzyme | 2022 | Mauro Marengo, Davide Pezzilli, Eleonora Gianquinto, Alex Fissore, Simonetta Oliaro-Bosso, Barbara Sgorbini, Francesca Spyrakis, Salvatore Adinolfi | |
| Exploring Ligand Binding Domain Dynamics in the NRs Superfamily | 2022 | D'Arrigo, Giulia; Autiero, Ida; Gianquinto, Eleonora; Siragusa, Lydia; Baroni, Massimo; Cruciani, Gabriele; Spyrakis, Francesca | |
| Fluorescent Nitric Oxide Photodonors Based on BODIPY and Rhodamine Antennae | 2019 | Parisi C.; Failla M.; Fraix A.; Rolando B.; Gianquinto E.; Spyrakis F.; Gazzano E.; Riganti C.; Lazzarato L.; Fruttero R.; Gasco A.; Sortino S. | |
| In the search for new NLRP3 inhibitors: chemical modulation of the 1-(piperidin-4-yl)-1,3-dihydro-2 Hbenzo[d]imidazole-2-one scaffold | 2021 | Simone Gastaldi, Valentina Boscaro, Eleonora Gianquinto, Christina F. Sandall, Marta Giorgis, Elisabetta Marini, Federica Blua, Margherita Gallicchio, Francesca Spyrakis, Justin A. MacDonald, Massimo Bertinaria | |
| Interaction of human hemoglobin and semi-hemoglobins with the Staphylococcus aureus hemophore IsdB: a kinetic and mechanistic insight | 2019 | Gianquinto E.; Moscetti I.; De Bei O.; Campanini B.; Marchetti M.; Luque F.J.; Cannistraro S.; Ronda L.; Bizzarri A.R.; Spyrakis F.; Bettati S. | |
| Investigation into the Use of Encorafenib to Develop Potential PROTACs Directed against BRAFV600E Protein | 2022 | Marini, Elisabetta; Marino, Marco; Gionfriddo, Giulia; Maione, Federica; Pandini, Marta; Oddo, Daniele; Giorgis, Marta; Rolando, Barbara; Blua, Federica; Gastaldi, Simone; Marchiò, Serena; Kovachka, Sandra; Spyrakis, Francesca; Gianquinto, Eleonora; Di Nicolantonio, Federica; Bertinaria, Massimo | |
| Iron metabolism at the interface between host and pathogen: From nutritional immunity to antibacterial development | 2020 | Marchetti M.; De Bei O.; Bettati S.; Campanini B.; Kovachka S.; Gianquinto E.; Spyrakis F.; Ronda L. | |
| N-[1,3-Dialkyl(aryl)-2-oxoimidazolidin-4-ylidene]-aryl(alkyl)sulphonamides as Novel Selective Human Cannabinoid Type 2 Receptor (hCB2R) Ligands; Insights into the Mechanism of Receptor Activation/Deactivation | 2022 | Gianquinto, Eleonora; Sodano, Federica; Rolando, Barbara; Kostrzewa, Magdalena; Allarà, Marco; Mahmoud, Ali Mokhtar; Kumar, Poulami; Spyrakis, Francesca; Ligresti, Alessia; Chegaev, Konstantin | |
| Natural products as novel scaffolds for the design of glycogen synthase kinase 3β inhibitors | 2022 | Montanari, Serena; Seidl, Claudia; Davani, Lara; Gianquinto, Eleonora; Emrichova, Eliska; Terenzi, Cristina; Andrisano, Vincenza; De Simone, Angela | |
| NLRP3 monomer functional dynamics: From the effects of allosteric binding to implications for drug design | 2023 | Casali, Emanuele; Serapian, Stefano A; Gianquinto, Eleonora; Castelli, Matteo; Bertinaria, Massimo; Spyrakis, Francesca; Colombo, Giorgio | |
| Repurposing the trypanosomatidic gsk kinetobox for the inhibition of parasitic pteridine and dihydrofolate reductases | 2021 | Santucci M.; Luciani R.; Gianquinto E.; Pozzi C.; Di Pisa F.; Dello Iacono L.; Landi G.; Tagliazucchi L.; Mangani S.; Spyrakis F.; Costi M.P. | |
| Selective delivery of pentamidine toward cancer cells by self-assembled nanoparticles | 2022 | Andreana, I; Gazzano, E; Gianquinto, E; Piatti, G; Bincoletto, V; Kryza, D; Lollo, G; Spyrakis, F; Riganti, C; Arpicco, S; Stella, B |