We have assessed the different adhesive properties of some of the most common bacteria associated with periprosthetic joint infection on various types of ultra high molecular Weight Polyethylene (UHMWPE). Quantitative in vitro analysis of the adhesion of biofilm producing strains of Staphylococcus aureus and Escherichia coli to physically and chemically characterised standard UHMWPE (PE), vitamin E blended UHMWPE (VE-PE) and oxidised UHMWPE (OX-PE) was performed using a sonication protocol. A significant decreased bacterial adhesion was registered for both strains on VE-PE, in comparison with that observed on PE, within 48 hours of observation (S. aureus p = 0.024 and E. coli p = 0.008). Since Vitamin E reduces bacterial adhesive ability, VE-stabilised UHMWPE could be valuable in joint replacement by presenting excellent mechanical properties, while reducing bacterial adhesiveness.

Interplay between surface properties of standard, vitamin E blended and oxidised ultra high molecular weight polyethylene used in total joint replacement and adhesion of Staphylococcus aureus and Escherichia coli [*V.Allizond is the corresponding author]

BANCHE, Giuliana
First
;
ALLIZOND, VALERIA
;
BRACCO, Pierangiola;BOFFANO, MICHELE;BRACH DEL PREVER, Elena Maria;CUFFINI, Annamaria
Last
2014

Abstract

We have assessed the different adhesive properties of some of the most common bacteria associated with periprosthetic joint infection on various types of ultra high molecular Weight Polyethylene (UHMWPE). Quantitative in vitro analysis of the adhesion of biofilm producing strains of Staphylococcus aureus and Escherichia coli to physically and chemically characterised standard UHMWPE (PE), vitamin E blended UHMWPE (VE-PE) and oxidised UHMWPE (OX-PE) was performed using a sonication protocol. A significant decreased bacterial adhesion was registered for both strains on VE-PE, in comparison with that observed on PE, within 48 hours of observation (S. aureus p = 0.024 and E. coli p = 0.008). Since Vitamin E reduces bacterial adhesive ability, VE-stabilised UHMWPE could be valuable in joint replacement by presenting excellent mechanical properties, while reducing bacterial adhesiveness.
96-B
4
497
501
Bacterial adhesion; Escherichia coli; Oxidation.; Staphylococcus aureus; UHMWPE; Vitamin E
Banche G; Allizond V*; Bracco P; Bistolfi A; Boffano M; Cimino A; Brach del Prever EM; Cuffini AM
File in questo prodotto:
File Dimensione Formato  
BJJ_2014 aperto.pdf

Accesso aperto

Tipo di file: POSTPRINT (VERSIONE FINALE DELL’AUTORE)
Dimensione 921.54 kB
Formato Adobe PDF
921.54 kB Adobe PDF Visualizza/Apri
Banche 2014 BJJ_Br.pdf

Accesso riservato

Tipo di file: PDF EDITORIALE
Dimensione 1.22 MB
Formato Adobe PDF
1.22 MB Adobe PDF   Visualizza/Apri   Richiedi una copia

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2318/143648
Citazioni
  • ???jsp.display-item.citation.pmc??? 15
  • Scopus 33
  • ???jsp.display-item.citation.isi??? 34
social impact