The hematological and cytogenetical studies of a case of atypical myeloproliferative disorder are reported. The patient displayed moderate leukocytosis, anemia and thrombocytopenia. Reduced or absent growth of CFU-C was observed in the bone marrow and peripheral blood. The cytogenetical analysis revealed a trisomy 21 limited to the neoplastic clone. The overall results are discussed and compared with the rare cases of acquired trisomy 21 reported in the literature.

Atypical myeloproliferative disorder associated with a 21 trisomic clone.

AGLIETTA, Massimo;PIACIBELLO, Vanda;DE MARCHI, Mario;
1981-01-01

Abstract

The hematological and cytogenetical studies of a case of atypical myeloproliferative disorder are reported. The patient displayed moderate leukocytosis, anemia and thrombocytopenia. Reduced or absent growth of CFU-C was observed in the bone marrow and peripheral blood. The cytogenetical analysis revealed a trisomy 21 limited to the neoplastic clone. The overall results are discussed and compared with the rare cases of acquired trisomy 21 reported in the literature.
Apr-Jun;11(2)
111
115
PONZIO G ;AGLIETTA M ;PIACIBELLO W ;DE MARCHI M ;CARBONARA AO
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2318/30699
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