Polyomavirus-associated nephropathy is one of the most common viral complications in renal transplant recipients. Viral replication is the single common feature of all patients at risk of nephropathy. Therefore, screening for virus replication allows for the identification of patients at risk of developing nephropathy and permits earlier intervention, in particular a pre-emptive reduction of immunosuppression, with improvement of outcome. This paper describes the modes of virological monitoring and its role in the clinical management of renal transplant patients.

Polyomavirus-associated nephropathy: critical issues in virological monitoring

CAVALLO, Rossana;BERGALLO, Massimiliano;SIDOTI, Francesca;TERLIZZI, Maria Elena;Costa C.
2009

Abstract

Polyomavirus-associated nephropathy is one of the most common viral complications in renal transplant recipients. Viral replication is the single common feature of all patients at risk of nephropathy. Therefore, screening for virus replication allows for the identification of patients at risk of developing nephropathy and permits earlier intervention, in particular a pre-emptive reduction of immunosuppression, with improvement of outcome. This paper describes the modes of virological monitoring and its role in the clinical management of renal transplant patients.
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BKV; JCV; SV40; Polyomavirus-associated nephropathy; Renal transplantation
Cavallo R; Bergallo M; Sidoti F; Astegiano S; Terlizzi ME; Costa C.
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2318/65950
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